294 Stem Cell Enriched Fat Grafts Versus Autologous Fat Grafts for Facial Reconstruction: A Systematic Review and Meta-Analysis
نویسندگان
چکیده
Abstract Aim To compare the results of stem cell-enhanced fat grafting to autologous for face reconstruction. Method A systematic review and meta-analysis were carried out in accordance with Preferred Reporting Items Systematic Reviews Meta-analyses (PRISMA) Guidelines, an electronic search was identify all Randomised Controlled Trials (RCTs), case control studies, cohort studies comparing outcomes cell-enrichment versus routine facial The primary outcome measures volume retention infection rate. Secondary included post-surgery patient satisfaction, redness swelling, necrosis, cysts, operation time. For analysis, fixed random effects modelling utilised. Results Eight a total 275 participants assessed. In terms mean retention, there significant difference between groups (standardised Mean Difference [MD] = 2.49, P 0.00001). However, no rates two (OR 0.36, 0.30). Except duration, which shorter latter, intervention group had similar secondary outcomes. Conclusions When compared conventional grafting, cell-enriched is better alternative reconstruction surgery since it enhances does not worsen satisfaction or surgical complications.
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ژورنال
عنوان ژورنال: British Journal of Surgery
سال: 2022
ISSN: ['1365-2168', '0007-1323']
DOI: https://doi.org/10.1093/bjs/znac269.301